| Medicine Name | Jardiance 10 mg |
| Generic Name | Empagliflozin 10mg |
| Manufacturer | Boehringer Ingelheim India Pvt Ltd |
| Indicated For | Adults with type 2 diabetes, heart failure, or chronic kidney disease (CKD) |
| Primary Use | Manage blood sugar in Type 2 Diabetes |
| Additional Uses | Reduce risk of cardiovascular complications, heart failure, and CKD |
| Mechanism | Promotes glucose excretion via urine (SGLT2 inhibitor) |
| Dose | 10 mg once daily (can be increased to 25 mg if needed) |
What is Jardiance 10 mg?
Jardiance 10 mg contains Empagliflozin, a prescription medication used to manage type 2 diabetes, heart failure, and chronic kidney disease (CKD). It belongs to a class of drugs called SGLT-2 inhibitors, which work by promoting the removal of excess glucose through the urine.
Manufactured by Boehringer Ingelheim and Eli Lilly, Jardiance helps lower blood sugar levels and reduces the risk of cardiovascular events in adults.
Key Medical Uses of Jardiance 10 mg
- Type 2 Diabetes: Helps regulate blood sugar levels alongside diet and exercise.
- Heart Failure: Reduces risk of cardiovascular death and hospitalization in adults.
- Kidney Disease: Slows down the progression of CKD and reduces renal events.
How Jardiance Works (Mechanism of Action)
Jardiance blocks the Sodium-Glucose Cotransporter-2 (SGLT2) in the kidneys. This results in:
- Reduced glucose reabsorption
- Increased urinary glucose excretion
- Improved glycemic control
- Lower blood pressure and body weight (indirect benefits)
Dosage Guidelines
- Starting Dose: 10 mg once daily, with or without food.
- Max Dose: May be increased to 25 mg if additional glucose control is needed.
- Timing: Take at the same time each day for best results.
- Missed Dose: Take as soon as you remember, unless it’s close to your next dose.
Possible Side Effects of Jardiance
Common:
- Genital yeast infections (especially in women)
- Urinary tract infections (UTIs)
- Increased urination
- Dehydration and dizziness
- Low blood sugar (if taken with insulin or sulfonylureas)
Serious (Rare):
- Ketoacidosis (even with normal blood sugar)
- Severe urinary tract infection
- Fournier’s gangrene (rare genital infection)
- Acute kidney injury
Seek emergency medical attention if you experience symptoms like confusion, vomiting, difficulty breathing, or swelling.
Important Precautions
- Kidney Function: Not recommended in patients with eGFR <30 mL/min/1.73m².
- Pregnancy & Breastfeeding: Avoid unless specifically prescribed.
- Alcohol: Can increase risk of dehydration or hypoglycemia.
- Surgery: May need to stop Jardiance before surgery or during acute illness.
Drug Interactions
- Diuretics: May increase risk of dehydration.
- Insulin or Sulfonylureas: Increases risk of hypoglycemia.
- Lithium: May require dose adjustment.
- Always inform your doctor of all medications and supplements you’re taking.
Who Should Avoid Jardiance?
- Patients with type 1 diabetes
- Those with a history of diabetic ketoacidosis
- Individuals with severe renal impairment
- Pregnant or breastfeeding women without doctor’s approval
FAQs about Jardiance 10 mg
Q1. Is Jardiance safe long-term?
Yes, clinical trials support long-term cardiovascular and renal benefits, but regular monitoring is essential.
Q2. Can Jardiance be taken at night?
Yes, but it’s usually recommended in the morning to reduce nighttime urination.
Q3. Is Jardiance used for weight loss?
While not approved for weight loss, patients may experience weight reduction as a secondary effect.
Q4. Can Jardiance be used in combination with metformin?
Yes, it is commonly prescribed alongside metformin for improved glycemic control.